Life Sciences Portfolio

  • AneuRx

    Stent grafts for abdominal aortic aneurysm

    Acquired by Medtronic (MDT)

  • Arbor Health Care

    Skilled nursing and subacute care centers

    Acquired by Extendicare (EXE)

  • Ardian

    Catheter-based treatment for hypertension

    Acquired by Medtronic

  • Athena Neurosciences

    Pharmaceuticals for neurological diseases

    Acquired by Elan Corp., plc
    (ELN)

  • Avidia

    New protein structural motifs for treating human disease.

    Acquired by Amgen (AMGN)

  • Cabochon Aesthetics

    A medical device company developing effective scientific solutions for aesthetic procedures.

    PRIVATE

  • Calithera Biosciences

    A new class of anti-cancer therapeutics based on activation of caspases

  • Cardiomind, Inc.

    Stents for small diameter and distal hard-to-reach coronary vessels.

    PRIVATE

  • CardioThoracic Systems

    Devices for minimally-invasive heart surgery

    Acquired by Guidant (GDT)

  • CareMedic

    Revenue cycle management systems for hospitals

    PRIVATE

  • Catalyst Biosciences

    Developer of engineered proteases as protein therapeutics that attack targets which cause disease.

    PRIVATE

  • Coalescent Surgical

    Devices for automating tissue attachment

    PRIVATE

  • Elcelyx Therapeutics

    Elcelyx is a biotechnology company that is creating new therapeutics for the treatment of diabetes and obesity

  • Embol-X

    Devices to protect the brain from stroke

    Acquired by Edwards Lifesciences (EW)

  • FoldRx Pharmaceuticals

    Treatments for diseases caused by misfolding of specific proteins

    Acquired by Pfizer

  • ForSight Labs

    Ophthalmic incubator creating unique solutions that address unmet clinical needs in diseases of the eye.

    PRIVATE

  • ForSight Vision4

    Developer of innovative drug delivery platform for ophthalmic use

  • ForSight Vision5

    Developing novel device solutions for ophthalmic diseases

  • Galleon Pharmaceuticals

    Innovative medicines for pulmonology, neurology, cardiology, sleep medicine and pediatrics

    PRIVATE

  • Gliatech

    Devices for the treatment of the nervous system

    (GLIA)

  • GlobeImmune

    Therapeutic vaccine platform technology targeting infectious disease and cancer

    PRIVATE

  • Holaira

    Novel devices for treating lung diseases

  • Intact Medical

    Develops minimally invasive RF-based surgical instruments for biopsy

    PRIVATE

  • IPC – The Hospitalist Company

    Hospital-based physician practice management company

    (IPCM)

  • Kona Medical

    Develops a novel, non-invasive technology for the treatment of hypertension (HTN)

  • LuMend

    Devices for treating chronic total occlusions

    PRIVATE

  • Medaphis

    Business management services for hospitals/physicians

    Acquired by Per-Sé (PSTI)

  • Miramar

    Device for the treatment of hyperhidrosis and aesthetic complications of excessive sweating

    PRIVATE

  • Morphotek, Inc.

    Next generation antibodies production technology.

    Acquired by EISIA

  • Mosaic Biosciences

    Platform for tissue engineering using synthetic smart polymers

  • Moximed

    An innovative treatment for patients with osteoarthritis

    PRIVATE

  • NaZura

    NaZura BioHealth Inc. is focused on developing consumer and pharmaceutical products based on its proprietary Gut Sensory Modulation (GSM) technology.

  • NeuroControl

    Devices for the treatment of neuromuscular disorders

    PRIVATE

  • Nexis Vision

    Developer of ophthalmic device to reduce post-refractive surgery pain and improve visual acuity

  • OncoMed Pharmaceuticals Inc.

    Biological therapeutics targeting cancer stem cells

    PRIVATE

  • Optiscan Biomedical Corporation

    Instruments and sensors for accurate, automated measurement of blood glucose levels

    PRIVATE

  • Orexigen

    Developer of drug treatments for obesity and related disorders.

    (OREX)

  • Perclose

    Suture-mediated vascular closure systems

    Acquired by Abbott Labs (ABT)

  • Principia

    Drug discovery company based on a proprietary chemistry platform that generates novel compounds with enhanced selectivity, high potency and longer duration of effect

  • Promedior Pharmaceuticals

    Therapeutics to treat fibrosis

    PRIVATE

  • Ra Pharmaceuticals

    Platform for orally available and cell permeable biologics

  • Relievant Medsystems

    Relievant Medsystems is developing a treatment for lower back pain

    PRIVATE

  • Replidyne

    Drug discovery and development focused on a new class of antibiotics

    (RDYN)

  • Ribozyme Pharmaceuticals

    RNA-based pharmaceuticals for human disease

    (RZYM)

  • Scioderm

    Scioderm is focused on the development of innovative drugs for the treatment of chronic diseases of the skin.

  • Second Genome

    Microbiome-based therapeutics for infection, inflammation, and metabolic disease

  • Sequana Therapeutics

    Gene discovery via functional genomics

    Acquired by Axys Pharmaceutical (AXPH)

  • SetPoint Medical

    Neuro-modulation platform for the treatment of a variety of acute and chronic diseases

    PRIVATE

  • SONIC Innovations

    Digital hearing aids

    (SNCI)

  • Spine Wave, Inc.

    Novel devices for spine surgery

    PRIVATE

  • Stemgent

    Reagents for stem cell researchers

    PRIVATE

  • The Foundry

    Medical device incubator

    PRIVATE

  • Thermage

    Devices for cosmetic aesthetic surgery

    (THRM)

  • Third Millenium Healthcare Systems

    Internet-based workflow solutions for healthcare organizations

    Merged with CareMedic

  • Threshold Pharmaceutical, Inc.

    Developing targeted therapies for treatment of cancer.

    (THLD)

  • Tragara Pharmaceuticals

    Developer of drugs for the treatment of cancer and inflammation-related diseases.

    PRIVATE

  • Transcend

    Ophthalmic devices for diseases of the eye

    PRIVATE

  • Trellis Bioscience

    Platform technology for monoclonal antibody development and production

    PRIVATE

  • Twelve

    Developing a novel device for treatment of chronic cardiovascular diseases

    PRIVATE

  • Vapotherm

    Vapotherm is developing high flow therapy for clinically effective respiratory support.

  • Vertiflex

    Implantable devices for treatment of chronic spinal disorders

    PRIVATE

  • Vical

    DNA-based pharmaceuticals for human disease

    (VICL)

  • XTENT

    Next-generation products designed to increase the market penetration of stents

    (XTNT)

All portfolio companies in active funds